How Do the Ingredients in Altitude RX Help Prevent Altitude Sickness?

3 min read

Altitude RX bottle under microscope

Our scientists used the most potent compounds available in amounts shown to prevent symptoms of Acute Mountain Sickness.


Science has demonstrated that Ginkgo biloba has a remarkable ability to increase blood flow throughout the body, enabling it to cope better with decreased atmospheric oxygen levels.[1],[2] Antioxidant properties in the leaf extract increase vasodilation and peripheral blood flow in the capillary vessels, as well as decreasing blood viscosity and helping to regulate cerebral energy metabolism.

A 2007 study[1] provides some of the most compelling data to date supporting the efficacy of Ginkgo biloba in prevention of altitude mountain sickness. A group taking Ginkgo biloba had no increase in their AMS score (which is remarkable), while acetazolamide and placebo groups showed increases of 36% and 54%, respectively. The authors concluded that their study provided evidence supporting the use of Ginkgo biloba in the prevention of AMS, demonstrating that 24 hours of pre-treatment with Ginkgo biloba and subsequent maintenance during exposure to high altitude are sufficient to reduce the incidence of AMS in participants with no previous high-altitude experience.


Vikings used rhodiola to enhance physical strength and endurance. Russians drink rhodiola tea as an energy booster. Sherpas have used it to climb Mt. Everest.
Rhodiola rosea has been categorized as an adaptogen due to its ability to increase resistance to a variety of chemical, biological and physical stressors, and to help the body to recover homeostasis.

With Altitude RX natural remedy for altitude sickness, you will feel less fatigued and have more energy, resulting in improved performance and endurance and a faster recovery time.*

Athletes have used Rhodiola to improve increase endurance and improve performance. It is also believed to increase strength and shorten recovery after strenuous and prolonged endurance events and workouts.

Rhodiola also has been shown to reverse the effects of asthenia. It reduces fatigue, labored breathing, rapid heart rate, sluggishness, and excessive sleeping.[3][4]

Alpha-Lipoic Acid (ALA), Vitamins C and E

When our bodies' cells use oxygen, they naturally produce free radicals as byproducts, which can cause cell damage. ALA, Vitamin C and Vitamin E work synergistically to protect cells from free radical damage.[5][6]

In a study of Mt. Everest climbers, antioxidant supplementation at high altitude was shown to be an effective intervention for reducing AMS and improving the physiological profile of mountaineers.[7]


Research Studies

[1]¬†Moraga FA, Flores A, Serra J, Esnaola C, Barriento C. Ginkgo biloba decreases acute mountain sickness in people ascending to high altitude at Ollag√ľe (3696 m) in northern Chile. Laboratorio de Fisiolog√≠a, Escuela de Medicina, Universidad Cat√≥lica del Norte. Wilderness Environ Med. 2007 Winter;18(4):251-7.

[2] Gertsch JH, Seto TB, Mor J, Onopa J. Ginkgo biloba for the prevention of severe acute mountain sickness (AMS) starting one day before rapid ascent. The University of Hawaii, John A. Burns School of Medicine, and the Kapiolani Clinical Research Center. H High Alt Med Biol.2002 Spring;3(1):29-37.

[3] Zhang ZH, Feng SH, Hu GD, Cao ZK, Wang LY. Effect of Rhodiola on preventing high altitude reactions. A comparison of cardiopulmonary function in villagers at various altitudes. Zhongguo Zhong Yao Za Zhi. 1989 Nov;14(11):687-90, 704.

[4] Zhang ZJ, Tong Y, Zou J, Chen PJ, Yu DH. Dietary supplement with a combination of Rhodiola crenulata and Ginkgo biloba enhances the endurance performance in healthy volunteers. Chin J Integr Med. 2009; 15:177-183.

[5]Zembron-Lacny A, Szyszka K, Szygula Z. (2007). Effect of cysteine derivatives administration in healthy men exposed to intense resistance exercise by evaluation of pro-antioxidant ratio. J Physiol Sci. 57(6):343-8.

[6] Marangon K, Devaraj S, Tirosh O, Packer L, Jialal I. (1999). Comparison of the effect of alpha-lipoic acid and alpha-tocopherol supplementation on measures of oxidative stress. Free Radic Biol Med. 27(9-10):1114-21.

[7] Damian M. Bailey, Bruce Davies. Acute Mountain Sickness; Prophylactic Benefits of Antioxidant Vitamin Supplementation at High Altitude. Hypoxia Research Unit, Health and Exercise Sciences Research Laboratory, School of Applied Sciences, University of Glamorgan, Pontypridd, South Wales, UK. High Altitude Medicine & Biology. March 2001, 2(1): 21-29. Published in Volume: 2 Issue 1: July 6, 2004.